Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 13 (Jun. 25, 2002), pp. 8554-8561 (8 pages) I-TevI, the phage T4 td intron-encoded endonuclease, ...
Zinc finger proteins (Zn is silver) coupled to FokI nuclease domains (central ribbon structures) bind to a targeted DNA sequence. Credit: Sangamo BioSciences Diversification—having railroads, hotels, ...
Zinc finger nucleases (ZFNs) have great potential for translational research and clinical use. Scientists succeeded in the efficient construction of functional ZFNs and the improvement of their genome ...
Researchers have developed a faster way to engineer synthetic enzymes that target specific DNA sequences for inactivation, repair or alteration. The method is a highly effective but less ...
Researchers at the University of Toronto and New York University have developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door toward ...
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